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16.07.2020, 12:28
Drugs or medical interventions are usually compared head-to-head in randomized controlled trials to identify the better option for treatment. Nowadays, multiple treatment options are available in many... mehr
17.07.2019, 16:28
In all topics related to medicine, expert interviews are extremely valuable to understand the complexly linked decisions that decide about the fate of medicines and medical devices in the market. The value... mehr
06.07.2018, 10:46
Contrary to the public media, scientific authors seem to prefer good news over bad ones. They cite studies with positive results significantly more often than studies reporting to have found nothing new. Is... mehr
20.09.2017, 15:12
The International Committee of Medical Journal Editors’ (ICMJE) plan for mandatory sharing of clinical trial data as prerequisite for publication in medical journals1 triggered mixed responses from the... mehr
13.01.2017, 12:44
The November 8th issue of the British Medical Journal (BMJ) features an article titled “60 seconds on TrialsTracker”. TrialsTracker is a website that reports the... mehr
29.03.2016, 13:14
Precision is always good, isn´t it? Especially in science, accurate and precise data and calculations are absolutely essential. But most of us might also have a feeling of “too much precision” when our pocket... mehr
11.08.2015, 12:07
Are you involved in the organisation or conduction of advisory boards? If so, from time to time you may wonder whether the results are proportionate to the money and time invested. Here are some thoughts about... mehr
24.07.2015, 14:28
An essay in the Journal of the Royal Society of Medicine by Alpers et al. (J R Soc Med 2015; 108: 8–10) titled “Evolution of evidence-based medicine to detect evidence mutations” seems to attach evolutionary... mehr
26.02.2015, 11:59
Assessing the relevance of a metaanalysis or any other systematic review, is no trivial task. Ultimately, its quality depends on the reliability of the included studies and a reasonable selection of studies... mehr
26.01.2015, 10:24
Everybody wants them, few have them – the „hard endpoints“ in clinical studies. What are these “hard endpoints” and is being “hard” relevant for endpoints that are used for developing messages from studies?... mehr
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